Rabbit Polyclonal Antibody to PARP1

包装: 1G|100G|500G|1KG|100KG

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别名:PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Specification
Aliases	PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
Entrez GeneID	142
Swissprot	P09874
WB Predicted band size	Calculated MW: 113 kDa; Observed MW: 116,24 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic peptide of human PARP
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application
WB	1/500-1/1000
IHC	1/50-1/100
FCM	1/50-1/100

	Western blot analysis of PARP in 293, Jurkat lysates using PARP1 antibody.
	Western blot analysis of PARP in Hela lysates using PARP antibody.
	Immunohistochemistry analysis of paraffin-embedded Human tonsil using PARP1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.