库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to PCDHA6

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别名:CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
应用:IHC
反应种属:Human
规格:50μl/100μl

Description
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Specification
Aliases CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
Swissprot Q9UN73
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic peptide of human PCDHA6
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/10-1/50
ELISA 1/1000-1/2000

The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P05615(PCDHA6 Antibody) at dilution 1/20. (Original magnification: ×200)

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。