别名:PCDH-GAMMA-B5应用:IHC
反应种属:Human
规格:50μl/100μl
| Description | 
|---|
| This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. | 
| Specification | |
|---|---|
| Aliases | PCDH-GAMMA-B5 | 
| Swissprot | Q9Y5G0 | 
| Host/Isotype | Rabbit IgG | 
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | 
| Species Reactivity | Human | 
| Immunogen | Synthetic peptide of human PCDHGB5 | 
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol | 
| Application | |
|---|---|
| IHC | 1/30-1/150 | 
| ELISA | 1/5000-1/10000 | 
|  | The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06299(PCDHGB5 Antibody) at dilution 1/40. (Original magnification: ×200) | 
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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