库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to PD L1

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别名:Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1, B7 homolog 1, B7-H1, CD274, CD274 (HGNC:17635)
应用:WB
反应种属:Human
规格:50μl/100μl

Description
Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443, PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).
Specification
Aliases Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1, B7 homolog 1, B7-H1, CD274, CD274 (HGNC:17635)
Entrez GeneID 29126
Swissprot Q9NZQ7
WB Predicted band size 33.3kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This PD L1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human PD L1.
Application
WB 1/500-1/1000

All lanes : Anti-PD L1 Antibody (C-Term) at 1:1000 dilution + Hela whole cell lysate

Lysates/proteins at 20 µg per lane.
Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ASP1615) at 1/15000 dilution.

Observed band size : 43 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

All lanes : Anti-PD L1 Antibody (C-Term) at 1:1000 dilution

Lane 1:Hela whole cell lysate
Lane 2:A549 whole cell lysate
Lane 3:A431 whole cell lysate
Lane 4:MCF-7 whole cell lysate

Lysates/proteins at 20 µg per lane.
Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ASP1615) at 1/15000 dilution.

Observed band size : 43 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.


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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。