别名:PDE4B; DPDE4; cAMP-specific 3′; 5′-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3′,5′-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3′,5′-cyclic phosphodiesterase 4D; DPDE3; PDE43应用:WB,IHC
反应种属:Human,Mouse,Rat
规格:50μl/100μl
Description |
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phosphodiesterase 4B(PDE4B) Homo sapiens This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014], |
Specification | |
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Aliases | PDE4B; DPDE4; cAMP-specific 3′; 5′-cyclic phosphodiesterase 4B; DPDE4; PDE32; PDE4C; DPDE1; cAMP-specific 3′,5′-cyclic phosphodiesterase 4C; DPDE1; PDE21; PDE4D; DPDE3; cAMP-specific 3′,5′-cyclic phosphodiesterase 4D; DPDE3; PDE43 |
Entrez GeneID | 5144 |
Swissprot | Q07343/Q08493/Q08499 |
WB Predicted band size | 76kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | The antiserum was produced against synthesized peptide derived from human PDE4D around the phosphorylation site of Ser190/53. AA range:156-205 |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application | |
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WB | 1/500 – 1/2000 |
IHC | 1/100 – 1/300 |
ELISA | 1/20000 |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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