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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to PDE8A (L572)

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别名:High affinity cAMP-specific and IBMX-insensitive 3′,5′-cyclic phosphodiesterase 8A, PDE8A
应用:WB,IHC
反应种属:Human
规格:50μl/100μl

Description
PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
Specification
Aliases High affinity cAMP-specific and IBMX-insensitive 3′,5′-cyclic phosphodiesterase 8A, PDE8A
Entrez GeneID 5151
Swissprot O60658
WB Predicted band size 93.3kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Application
WB 1/1000
IHC 1/100-1/500

Western blot analysis of PDE8A Antibody (Center) (L572) (Cat# P30196) in HL60 cell line lysates (35ug/lane). PDE8A (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PDE8A antibody (Center) (L572)(Cat.#P30196), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。