中文 
别名:CD140a; PDGFR-alpha; PGFRA; kinase PDGFR-alpha;应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Rikova K, et al. (2007) Cell 131, 1190-203 Moritz A, et al. (2010) Sci Signal 3, ra64 Guo A, et al. (2008) Proc Natl Acad Sci U S A 105, 692-7 |
| Specification | |
|---|---|
| Aliases | CD140a; PDGFR-alpha; PGFRA; kinase PDGFR-alpha; |
| Entrez GeneID | 5156; |
| Swissprot | P16234 |
| WB Predicted band size | 140kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine849(S-N-Y(p)-V-S) derived from Human PDGFRa. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from 293 tissue using PDGFRa (Phospho-Tyr849) antibody P40552.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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