中文 
别名:CAP70; CLAMP; PDZD1; NHERF3; NHERF-3应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. |
| Specification | |
|---|---|
| Aliases | CAP70; CLAMP; PDZD1; NHERF3; NHERF-3 |
| Entrez GeneID | 5174; |
| Swissprot | Q5T2W1 |
| WB Predicted band size | 57kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Fusion protein of human PDZK1 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/25-1/100 |
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Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Mouse kidney tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds |
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Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using P43415 at dilution 1/20. |
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Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using P43415 at dilution 1/20. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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