Rabbit Polyclonal Antibody to PEBP1

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别名:PBP; HCNP; PEBP; RKIP; HCNPpp; PEBP-1
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Phosphatidylethanolamine-binding protein 1 is a protein that in humans is encoded by the PEBP1 gene. Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.

Description

Phosphatidylethanolamine-binding protein 1 is a protein that in humans is encoded by the PEBP1 gene. Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.

Specification
Aliases	PBP; HCNP; PEBP; RKIP; HCNPpp; PEBP-1
Swissprot	P30086
WB Predicted band size	21 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human PEBP1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1/1000-1/5000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: A549 cells, K562 cells, hela cells, hepG2 cells, Primary antibody: P07551(PEBP1 Antibody) at dilution 1/475, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07551(PEBP1 Antibody) at dilution 1/50. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P07551(PEBP1 Antibody) at dilution 1/50. (Original magnification: ×200)