别名:PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
| Description |
|---|
| Peptidoglycan recognition proteins (PGRPs) are molecules that recognize peptidoglycan, a large component in bacterial cell walls. In insects, PGRPs activate antimicrobial pathways, and in mammals PGRPs function as antibacterial neutrophil proteins. PGRP-L halts bacterial growth by acting as an alanine amidase, an enzyme that hydrolyzes the amide bond of bacterial peptidoglycan. PGRP-Iå and PGRP-I∫ are also members of the PGRP family that help recognize bacteria by binding to peptidoglycan and Gram-positive bacteria, but they do not have amidase activity. PGRP-S participates in intracellular killing of Gram-positive bacteria by stimulating two antimicrobial defense systems, the prophenoloxidase cascade and the antimicrobial peptides through Toll receptors. |
| Specification | |
|---|---|
| Aliases | PGRP; TAG7; PGRPS; PGLYRP; PGRP-S; TNFSF3L |
| Swissprot | O75594 |
| WB Predicted band size | 22 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human PGLYRP1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| ELISA | 1/1000-1/2000 |
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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, K562 cells, human fetal liver tissue, Primary antibody: P05158(PGLYRP1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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