别名:ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| The product of this gene is an essential component of the DNA damage checkpoint, and binds to single-stranded DNA coated with replication protein A that accumulates at sites of DNA damage. The encoded protein interacts with the ataxia telangiectasia and Rad3 related protein, a checkpoint kinase, resulting in accumulation of the kinase at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Specification | |
|---|---|
| Aliases | ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1 |
| Entrez GeneID | 84126 |
| Swissprot | Q8WXE1 |
| WB Predicted band size | 85.8kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This ATRIP Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S239 of human ATRIP. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Application | |
|---|---|
| WB | DB: 1/500 |
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Dot blot analysis of Phospho-ATRIP-S239 Antibody Phospho-specific Pab (Cat. #P31283) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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