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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to Phospho-CCNB3(T280)

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别名:G2/mitotic-specific cyclin-B3, CCNB3, CYCB3
应用:WB
反应种属:Human
规格:50μl/100μl

Description
The protein encoded by this gene belongs to the highly
conserved cyclin family, whose members are characterized by a
dramatic periodicity in protein abundance through the cell cycle.
Cyclins function as regulators of CDK kinases. Different cyclins
exhibit distinct expression and degradation patterns which
contribute to the temporal coordination of each mitotic event.
Studies of similar genes in chick and Drosophila suggest that this
cyclin may associate with CDC2 and CDK2 kinases, and be required
for proper spindle reorganization and restoration of the interphase
nucleus. Two transcript variants encoding different isoforms have
been found for this gene.
Specification
Aliases G2/mitotic-specific cyclin-B3, CCNB3, CYCB3
Entrez GeneID 85417
Swissprot Q8WWL7
WB Predicted band size 157.9kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This CCNB3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T280 of human CCNB3.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Application
WB DB: 1/500

Dot blot analysis of CCNB3 Antibody (Phospho T280) Phospho-specific Pab (Cat. #P32417) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。