Rabbit Polyclonal Antibody to Phospho-CD31 (Tyr713)

包装: 1G|100G|500G|1KG|100KG

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别名:Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA’; PECA1; CD antigen CD31
应用:WB,IHC,ICC
反应种属:Human,Mouse
规格：50μl/100μl

Description
PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Description

PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Specification
Aliases	Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA’; PECA1; CD antigen CD31
Entrez GeneID	5175
Swissprot	P16284
WB Predicted band size	Calculated MW: 83 kDa; Observed MW: 150 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	The antiserum was produced against synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyr713. AA range:686-735
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ICC	1/50-1/200
ELISA	1/10000

	EnzymeLinked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phospho-peptide (Phospho-left) and NonPhospho-peptide (Phospho-right), using PECAM1 (Phospho-Tyr71antibody
	Western blot analysis of Phospho-CD31 (Tyr713) in HepG2 lysates using Phospho-CD31 (Tyr713) antibody.The lane on the right is blocked with the Phospho- peptide.
	Immunofluorescence analysis of Phospho-CD31 (Tyr713) in HeLa using Phospho-CD31 (Tyr713) antibody. The picture on the right is blocked with the Phospho- peptide.