别名:Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, 2.7.11.20, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EEF2K应用:WB
反应种属:Human
规格:50μl/100μl
Description |
---|
Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. |
Specification | |
---|---|
Aliases | Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, 2.7.11.20, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, EEF2K |
Entrez GeneID | 29904 |
Swissprot | O00418 |
WB Predicted band size | 82.1kDa |
Host/Isotype | Rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This Phospho-eEF2k (Ser366) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 337-371 amino acids from the human region of human EEF2k. |
Application | |
---|---|
WB | 1/500 |
![]() |
Western blot analysis of lysates from Hela cell line, untreated or treated with 10% FBS, using 456632102(Cat. #P34404)(upper) or Beta-actin (lower). |
![]() |
Western blot analysis of lysates from Hela cell line, untreated or treated with TPA, 200nM, using (Cat. #P34404)(upper) or Beta-actin (lower). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复