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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to Phospho-mouse TSC1(S312)

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别名:Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
应用:WB
反应种属:Mouse
规格:50μl/100μl

Description
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Specification
Aliases Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Entrez GeneID 64930
Swissprot Q9EP53
WB Predicted band size 128.7kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of mouse TSC1.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Application
WB DB: 1/500

Dot blot analysis of mouse TSC1 Antibody (Phospho S312) Phospho-specific Pab (Cat. #P32389) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。