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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to Phospho-Src (Tyr419)

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别名:SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
应用:WB,FCM
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).
Specification
Aliases SRC; SRC1; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; p60-Src
Entrez GeneID 6714
Swissprot P12931
WB Predicted band size Calculated MW: 60 kDa; Observed MW: 60 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human Phospho-Src (Y419)
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/1000
FCM 1/50-1/100

Western blot analysis of Phospho-Src (Y419) in A431 lysates treated with pervanadate using Phospho-Src (Tyr419) antibody.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。