Rabbit Polyclonal Antibody to Phospho-Syk (Tyr323)

包装: 1G|100G|500G|1KG|100KG

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别名:SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk
应用:WB,IHC,ICC,FCM
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk
Entrez GeneID	6850
Swissprot	P43405
WB Predicted band size	Calculated MW: 72 kDa; Observed MW: 72 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Tyr323 of human Syk
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA