Rabbit Polyclonal Antibody to Phospho-Syk (Tyr348)

包装: 1G|100G|500G|1KG|100KG

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别名:SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk
应用:WB,IHC
反应种属:Human,Mouse,Rat,Monkey
规格：50μl/100μl

Description
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Description

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk
Entrez GeneID	6850
Swissprot	P43405
WB Predicted band size	Calculated MW: 72 kDa; Observed MW: 72 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Monkey
Immunogen	Synthetic peptide of human SYK
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ELISA	1/10000

	Western blot analysis of Phospho-Syk (Tyr348) in 3T3 lysates using Phospho-Syk (Tyr348) antibody.
	Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-Syk (Tyr348) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.