别名:YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格:50μl/100μl
| Description |
|---|
| YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. |
| Specification | |
|---|---|
| Aliases | YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65 |
| Entrez GeneID | 10413 |
| Swissprot | P46937 |
| WB Predicted band size | Calculated MW: 54 kDa; Observed MW: 65 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human YAP1 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| ICC | 1/100-1/200 |
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Western blot analysis of Phospho-YAP (Ser127) in COS7 lysates using Phospho-YAP (Ser127) antibody. |
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Immunofluorescence analysis of Phospho-YAP (Ser127) in Hela cells using YAP (Phospho- Ser127) antibody(green) and beta-tubulin antibody(green). |
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Immunohistochemistry analysis of paraffin-embedded Human heart using YAP (Phospho-Ser127) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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