Rabbit Polyclonal Antibody to PHTF2

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别名:
应用:IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
PHTF2 (putative homeodomain transcription factor 2) is a 785 amino acid protein that contains one basic helix-loop-helix (bHLH) domain and belongs to the PHTF family. Homologous to PHTF1, PHTF2 exhibits strongest similarity within putative homeodomains and both N- and C-terminal regions. Existing as four alternatively spliced isoforms, PHTF2 localizes to nucleus and participates in DNA binding. PHTF2 may also play a role in transcriptional regulation. While PHTF1 is expressed mainly in testis, PHTF2 is predominantly expressed in muscle, which suggests that both may have acquired different functions after their duplication and divergence. The gene that encodes PHTF2 maps to human chromosome 7q11.23.

Description

PHTF2 (putative homeodomain transcription factor 2) is a 785 amino acid protein that contains one basic helix-loop-helix (bHLH) domain and belongs to the PHTF family. Homologous to PHTF1, PHTF2 exhibits strongest similarity within putative homeodomains and both N- and C-terminal regions. Existing as four alternatively spliced isoforms, PHTF2 localizes to nucleus and participates in DNA binding. PHTF2 may also play a role in transcriptional regulation. While PHTF1 is expressed mainly in testis, PHTF2 is predominantly expressed in muscle, which suggests that both may have acquired different functions after their duplication and divergence. The gene that encodes PHTF2 maps to human chromosome 7q11.23.

Specification
Swissprot	Q8N3S3
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human PHTF2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/20-1/100
ELISA	1/2000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09067(PHTF2 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P09067(PHTF2 Antibody) at dilution 1/20. (Original magnification: ×200)