Rabbit Polyclonal Antibody to PIP5K1B

包装: 1G|100G|500G|1KG|100KG

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别名:MSS4; STM7
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I å, ∫, and ©, which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I å (designated PIPK I ∫ in mouse) is expressed in brain tissue . PIPK I ∫, designated PIPK I a in mouse, is also called STM7. PIPK I © has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.

Description

Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I å, ∫, and ©, which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I å (designated PIPK I ∫ in mouse) is expressed in brain tissue . PIPK I ∫, designated PIPK I a in mouse, is also called STM7. PIPK I © has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.

Specification
Aliases	MSS4; STM7
Swissprot	O14986
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human PIP5K1B
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/2000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08018(PIP5K1B Antibody) at dilution 1/30. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08018(PIP5K1B Antibody) at dilution 1/30. (Original magnification: ×200)