Rabbit Polyclonal Antibody to PIP5K1C

包装: 1G|100G|500G|1KG|100KG

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别名:LCCS3; PIPKIg_v4; PIP5Kgamma; PIP5K-GAMMA
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Description

This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

Specification
Aliases	LCCS3; PIPKIg_v4; PIP5Kgamma; PIP5K-GAMMA
Swissprot	O60331
WB Predicted band size	73 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human PIP5K1C
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/25-1/100
ELISA	1/2000-1/5000

	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A431 cells, hela cells, Primary antibody: P11513(PIP5K1C Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P11513(PIP5K1C Antibody) at dilution 1/25. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human brain tissue using P11513(PIP5K1C Antibody) at dilution 1/25. (Original magnification: ×200)