中文 
别名:KPCD; PKC-delta; PRKCD; kinase PKC-delta; nPKC-delta应用:WB
反应种属:Human,Rat
规格：50μl/100μl
| Description |
|---|
| Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Wie SM, et al. (2014)J Biol Chem. Adwan TS, et al. (2011)J Biol Chem 286, 35716-24. Lomonaco SL, et al. (2008) J Biol Chem 283, 17731-9. |
| Specification | |
|---|---|
| Aliases | KPCD; PKC-delta; PRKCD; kinase PKC-delta; nPKC-delta |
| Entrez GeneID | 5580; |
| Swissprot | Q05655 |
| WB Predicted band size | 78kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | Peptide sequence around phosphorylation site of Tyrosine 64 (H-I-Y(p)-E-G) derived from Human PKCD. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HepG2 cells treated with PMA using Phospho-PKCD (Tyr64) antibody P40561.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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