Rabbit Polyclonal Antibody to PLA2G2A

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别名:MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5′ UTRs have been found for this gene.

Description

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5′ UTRs have been found for this gene.

Specification
Aliases	MOM1; PLA2; PLA2B; PLA2L; PLA2S; PLAS1; sPLA2
Swissprot	P14555
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human PLA2G2A
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P03251(PLA2G2A Antibody) at dilution 1/55. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P03251(PLA2G2A Antibody) at dilution 1/55. (Original magnification: ×200)