中文 
别名:PLA2G4; cPLA2-alpha应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. |
| Specification | |
|---|---|
| Aliases | PLA2G4; cPLA2-alpha |
| Entrez GeneID | 5321; |
| Swissprot | P47712 |
| WB Predicted band size | 85kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein corresponding to residues near the N terminal of human phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/2000 |
| IHC | 1/50-1/200 |
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Gel: 8%SDS-PAGE Lysate: 40ug 293T cell Primary antibody: 1/750 dilution Secondary antibody dilution: 1/8000 Exposure time: 10 seconds |
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42819 at dilution 1/50. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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