别名:PLD 1; hPLD1; Choline phosphatase 1;应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.Hammond S.M., J. Biol. Chem. 272:3860-3868(1997) [PubMed: 9013646]Steed P.M., FASEB J. 12:1309-1317(1998) [PubMed: 9761774]Lopez I., J. Biol. Chem. 273:12846-12852(1998) [PubMed: 9582313] |
Specification | |
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Aliases | PLD 1; hPLD1; Choline phosphatase 1; |
Entrez GeneID | 5337; |
Swissprot | Q13393 |
WB Predicted band size | 120kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Peptide sequence around phosphorylation site of threonine 147(R-H-T(p)-F-R) derived from Human PLD1. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/1000 |
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Western blot analysis of extracts from HepG2 cells using PLD1 (Phospho-Thr147) Antibody P40517.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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