别名:P47应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
---|
Pleckstrin is highly expressed in human neutrophils. Pleckstrin is rapidly phosphorylated following treatment of neutrophils in response to inflammatory stimuli, probably by nonconventional PKC isoforms delta or zeta, which are expressed in human neutrophils. Phosphorylation by nonconventional PKC isoforms induces a conformational change in pleckstrin that promotes its interaction with membranes and/or with the cytoskeleton, serving to target proteins or lipids recognized by PH domains to sites where they can contribute to the microbicidal response. |
Specification | |
---|---|
Aliases | P47 |
Entrez GeneID | 5341; |
Swissprot | P08567 |
WB Predicted band size | 40kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human PLEK |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
---|---|
WB | 1/500-1/2000 |
IHC | 1/25-1/100 |
![]() |
Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Hela cell Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds |
![]() |
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P43427 at dilution 1/20. (Original magnification:x200) |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复