Rabbit Polyclonal Antibody to PLS1

包装: 1G|100G|500G|1KG|100KG

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别名:Plastin-1, Intestine-specific plastin, I-plastin, PLS1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5′ UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.

Description

Plastins are a family of actin-binding proteins that are
conserved throughout eukaryote evolution and expressed in most
tissues of higher eukaryotes. In humans, two ubiquitous plastin
isoforms (L and T) have been identified. The protein encoded by
this gene is a third distinct plastin isoform, which is
specifically expressed at high levels in the small intestine.
Alternatively spliced transcript variants varying in the 5′ UTR,
but encoding the same protein, have been found for this gene. A
pseudogene of this gene is found on chromosome 11.

Specification
Aliases	Plastin-1, Intestine-specific plastin, I-plastin, PLS1
Entrez GeneID	5357
Swissprot	Q14651
WB Predicted band size	70.3kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This PLS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 550-579 amino acids from the C-terminal region of human PLS1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	PLS1 Antibody (C-term) (Cat. #P31224) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PLS1 antibody detected the PLS1 protein (arrow).
	PLS1 Antibody (C-term) (Cat. #P31224)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLS1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.