别名:APR; NOXA应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
---|
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1?By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
Specification | |
---|---|
Aliases | APR; NOXA |
Entrez GeneID | 5366; |
Swissprot | Q13794 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Full length fusion protein |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
---|---|
IHC | 1/50-1/200 |
![]() |
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P42833 at dilution 1/50. |
![]() |
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using P42833 at dilution 1/50. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
发表回复