Rabbit Polyclonal Antibody to PMCH

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Pro-MCH, Neuropeptide-glycine-glutamic acid, NGE, Neuropeptide G-E, Neuropeptide-glutamic acid-isoleucine, NEI, Neuropeptide E-I, Melanin-concentrating hormone, MCH, PMCH, MCH
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
The melanin-concentrating hormone (MCH) is a cyclic neuropeptide isolated initially from salmon pituitary gland and later from rat hypothalamus (summarized by Nahon et al., 1992 [PubMed 1572663]). In mammals, MCH perikarya are confined largely to the lateral hypothalamus and zona incerta area with extensive neuronal projections throughout the brain, including the neurohypophysis. The anatomic distribution suggests a neurotransmitter or neuromodulator role for MCH in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. MCH and 2 other putative neuropeptides, NEI and NGE, are encoded by the same precursor and appear colocalized in nerve cells and in many instances within the projections. The precursor is designated pro-melanin-concentrating hormone (PMCH).

Description

The melanin-concentrating hormone (MCH) is a cyclic
neuropeptide isolated initially from salmon pituitary gland and
later from rat hypothalamus (summarized by Nahon et al., 1992
[PubMed 1572663]). In mammals, MCH perikarya are confined largely
to the lateral hypothalamus and zona incerta area with extensive
neuronal projections throughout the brain, including the
neurohypophysis. The anatomic distribution suggests a
neurotransmitter or neuromodulator role for MCH in a broad array of
neuronal functions directed toward the regulation of goal-directed
behavior, such as food intake, and general arousal. MCH and 2 other
putative neuropeptides, NEI and NGE, are encoded by the same
precursor and appear colocalized in nerve cells and in many
instances within the projections. The precursor is designated
pro-melanin-concentrating hormone (PMCH).

Specification
Aliases	Pro-MCH, Neuropeptide-glycine-glutamic acid, NGE, Neuropeptide G-E, Neuropeptide-glutamic acid-isoleucine, NEI, Neuropeptide E-I, Melanin-concentrating hormone, MCH, PMCH, MCH
Entrez GeneID	5367
Swissprot	P20382
WB Predicted band size	18.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This PMCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of human PMCH.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.