Rabbit Polyclonal Antibody to PMP22

包装: 1G|100G|500G|1KG|100KG

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别名:DSS; GAS3; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

Description

This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

Specification
Aliases	DSS; GAS3; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA
Swissprot	Q01453
WB Predicted band size	18 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human PMP22
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/200-1/1000
IHC	1/20-1/100
ELISA	1/5000-1/10000

	Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-7: Human cerebrum tissue, A172 cell, Mouse lung tissue, 293T cell, 231 cell, Mouse liver tissue, Mouse brain tissue lysates, Primary antibody: P06237(PMP22 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
	The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P06237(PMP22 Antibody) at dilution 1/20. (Original magnification: ×200)