Rabbit Polyclonal Antibody to POFUT1

包装: 1G|100G|500G|1KG|100KG

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别名:GDP-fucose protein O-fucosyltransferase 1, Peptide-O-fucosyltransferase 1, O-FucT-1, POFUT1, FUT12, KIAA0180
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq].

Description

This gene encodes a member of the glycosyltransferase
O-Fuc family. This enzyme adds O-fucose through an O-glycosidic
linkage to conserved serine or threonine residues in the epidermal
growth factor-like repeats of a number of cell surface and secreted
proteins. O-fucose glycans are involved in ligand-induced receptor
signaling. Alternative splicing of this gene results in two
transcript variants encoding different isoforms. [provided by
RefSeq].

Specification
Aliases	GDP-fucose protein O-fucosyltransferase 1, Peptide-O-fucosyltransferase 1, O-FucT-1, POFUT1, FUT12, KIAA0180
Entrez GeneID	23509
Swissprot	Q9H488
WB Predicted band size	44.0kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This POFUT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human POFUT1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	POFUT1 Antibody (C-term) (Cat. #P31146) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the POFUT1 antibody detected the POFUT1 protein (arrow).
	POFUT1 Antibody (C-term) (Cat. #P31146)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POFUT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.