Rabbit Polyclonal Antibody to POFUT2

包装: 1G|100G|500G|1KG|100KG

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别名:GDP-fucose protein O-fucosyltransferase 2, Peptide-O-fucosyltransferase 2, O-FucT-2, POFUT2, C21orf80, FUT13, KIAA0958
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).

Description

Fucose is typically found as a terminal modification of
branched chain glycoconjugates, but it also exists in direct
O-linkage to serine or threonine residues within cystine knot
motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or
thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an
O-fucosyltransferase that use THBS type-1 repeats as substrates
(Luo et al., 2006 [PubMed 16464857]).

Specification
Aliases	GDP-fucose protein O-fucosyltransferase 2, Peptide-O-fucosyltransferase 2, O-FucT-2, POFUT2, C21orf80, FUT13, KIAA0958
Entrez GeneID	23275
Swissprot	Q9Y2G5
WB Predicted band size	50.0kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This POFUT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the Central region of human POFUT2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	POFUT2 Antibody (Center) (Cat. #P31179) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the POFUT2 antibody detected the POFUT2 protein (arrow).
	POFUT2 Antibody (Center) (Cat. #P31179)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POFUT2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.