库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to POMC(Alpha-MSH)

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别名:LPH, MSH, NPP, POC, ACTH, CLIP
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation.
Specification
Aliases LPH, MSH, NPP, POC, ACTH, CLIP
Swissprot P01189
WB Predicted band size 29 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Synthetic peptide of human POMC
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/500-1/2000
ELISA 1/2000-1/5000

Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: P04121(POMC(Alpha-MSH) Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。