Rabbit Polyclonal Antibody to POMT1

包装: 1G|100G|500G|1KG|100KG

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别名:Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose–protein mannosyltransferase 1, POMT1
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.

Description

The protein encoded by this gene is an
O-mannosyltransferase that requires interaction with the product of
the POMT2 gene for enzymatic function. The encoded protein is found
in the membrane of the endoplasmic reticulum. Defects in this gene
are a cause of Walker-Warburg syndrome (WWS) and limb-girdle
muscular dystrophy type 2K (LGMD2K). Several transcript variants
encoding different isoforms have been found for this gene.

Specification
Aliases	Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose–protein mannosyltransferase 1, POMT1
Entrez GeneID	10585
Swissprot	Q9Y6A1
WB Predicted band size	84.9kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This POMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-735 amino acids from the C-terminal region of human POMT1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	POMT1 Antibody (C-term) (Cat. #P31077) western blot analysis in ZR-75-1,K562 cell line lysates (35ug/lane).This demonstrates the POMT1 antibody detected the POMT1 protein (arrow).
	POMT1 Antibody (C-term) (Cat. #P31077) western blot analysis in ZR-75-1,K562 cell line lysates (35ug/lane).This demonstrates the POMT1 antibody detected the POMT1 protein (arrow).
	POMT1 Antibody (C-term) (Cat. #P31077) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	POMT1 Antibody (C-term) (Cat. #P31077)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POMT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.