中文 
别名:activator of RNA decay; ARD-1; ARD1; EC 3.1.4.-; NIPP1应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. Isoform Gamma is a site-specific single-strand endoribonuclease that cleaves single strand RNA 3′ to purines and pyrimidines in A+U-rich regions. It generates 5′-phosphate termini at the site of cleavage. This isoform doesnot inhibit PP-1. May be implicated in mRNA splicing.Wang M., Proc. Natl. Acad. Sci. U.S.A. 91:10591-10595(1994).Van Eynde A., Eur. J. Biochem. 261:291-300(1999).Liu J.P., Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases. |
| Specification | |
|---|---|
| Aliases | activator of RNA decay; ARD-1; ARD1; EC 3.1.4.-; NIPP1 |
| Entrez GeneID | 5511; |
| Swissprot | Q12972 |
| WB Predicted band size | 40kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human PPP1R8. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
 |
Western blot analysis of extracts from Jurkat cells, using PPP1R8 antibody P42503. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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