别名:PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5′-GGTC[TC]CTAA-3′. |
| Specification | |
|---|---|
| Aliases | PR domain zinc finger protein 14, 211-, PR domain-containing protein 14, PRDM14 |
| Entrez GeneID | 63978 |
| Swissprot | Q9GZV8 |
| WB Predicted band size | 64.1kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This PRDM14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 128-163 amino acids from the N-terminal region of human PRDM14. |
| Application | |
|---|---|
| WB | 1/1000 |
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Western blot analysis of lysate from HepG2 cell line, using PRDM14 Antibody (N-term)(Cat. #P32921). P32921 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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