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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to PROC

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别名:Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide, PROC
应用:WB,IHC,ICC
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a vitamin K-dependent plasma
glycoprotein. The encoded protein is cleaved to its activated form
by the thrombin-thrombomodulin complex. This activated form
contains a serine protease domain and functions in degradation of
the activated forms of coagulation factors V and VIII. Mutations in
this gene have been associated with thrombophilia due to protein C
deficiency, neonatal purpura fulminans, and recurrent venous
thrombosis.
Specification
Aliases Vitamin K-dependent protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Vitamin K-dependent protein C light chain, Vitamin K-dependent protein C heavy chain, Activation peptide, PROC
Entrez GeneID 5624
Swissprot P04070
WB Predicted band size 52.1kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This PROC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human PROC.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000
IHC 1/100-1/500
ICC 1/10-1/50

All lanes : Anti-PROC Antibody (Center) at 1:500-1:1000 dilution
Lane 1: human liver lysate
Lane 2: human plasma lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 52 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

Confocal immunofluorescent analysis of PROC Antibody (Center) (Cat#P33905) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
PROC Antibody (Center) (Cat. #P33905)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PROC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。