Rabbit Polyclonal Antibody to PTHLH

包装: 1G|100G|500G|1KG|100KG

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别名:Parathyroid hormone-related protein, PTH-rP, PTHrP, Parathyroid hormone-like protein, PLP, PTHrP[1-36], PTHrP[38-94], Osteostatin, PTHrP[107-139], PTHLH, PTHRP
应用:WB,IHC,FCM
反应种属:Human, Mouse
规格：50μl/100μl

Description
PTHLH is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy.

Description

PTHLH is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy.

Specification
Aliases	Parathyroid hormone-related protein, PTH-rP, PTHrP, Parathyroid hormone-like protein, PLP, PTHrP[1-36], PTHrP[38-94], Osteostatin, PTHrP[107-139], PTHLH, PTHRP
Entrez GeneID	5744
Swissprot	P12272
WB Predicted band size	20.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This PTHLH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-103 amino acids from the Central region of human PTHLH.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	Western blot analysis of PTHLH antibody (Center) (Cat.#P30368) in mouse spleen tissue lysates (35ug/lane). PTHLH (arrow) was detected using the purified Pab.
	PTHLH Antibody (Center) (Cat. #P30368) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	PTHLH Antibody (Center) (Cat.#P30368) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PTHLH Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.