Rabbit Polyclonal Antibody to PTPLA (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, 3-hydroxyacyl-CoA dehydratase 1, HACD1, Cementum attachment protein, Protein-tyrosine phosphatase-like member A, PTPLA, HACD1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation.

Description

The protein encoded by this gene contains a characteristic
catalytic motif of the protein tyrosine phosphatases (PTPs) family.
The PTP motif of this protein has the highly conserved arginine
residue replaced by a proline residue; thus it may represent a
distinct class of PTPs. Members of the PTP family are known to be
signaling molecules that regulate a variety of cellular processes.
This gene was preferentially expressed in both adult and fetal
heart. A much lower expression level was detected in skeletal and
smooth muscle tissues, and no expression was observed in other
tissues. The tissue specific expression in the developing and adult
heart suggests a role in regulating cardiac development and
differentiation.

Specification
Aliases	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1, 3-hydroxyacyl-CoA dehydratase 1, HACD1, Cementum attachment protein, Protein-tyrosine phosphatase-like member A, PTPLA, HACD1
Entrez GeneID	9200
Swissprot	B0YJ81
WB Predicted band size	32.4kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This PTPLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PTPLA.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	PTPLA Antibody (N-term) (Cat. #P31293) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPLA antibody detected the PTPLA protein (arrow).
	PTPLA Antibody (N-term) (Cat. #P31293)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPLA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.