中文 
别名:DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA应用:IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Specification | |
|---|---|
| Aliases | DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA |
| Entrez GeneID | 5795; |
| Swissprot | Q12913 |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide corresponding to residues near the C terminal of human Protein tyrosine phosphatase, receptor type, J |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| IHC | 1/25-1/100 |
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Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using P42902 at dilution 1/40. |
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Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P42902 at dilution 1/40. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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