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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to PTPRN

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别名:Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, ICA3, ICA512
应用:WB
反应种属:Human
规格:50μl/100μl

Description
The protein encoded by this gene is a member of the
protein tyrosine phosphatase (PTP) family. PTPs are known to be
signaling molecules that regulate a variety of cellular processes
including cell growth, differentiation, mitotic cycle, and
oncogenic transformation. This PTP possesses an extracellular
region, a single transmembrane region, and a single catalytic
domain, and thus represents a receptor-type PTP. This PTP was found
to be an autoantigen that is reactive with insulin-dependent
diabetes mellitus (IDDM) patient sera, and thus may be a potential
target of autoimmunity in diabetes mellitus.
Specification
Aliases Receptor-type tyrosine-protein phosphatase-like N, R-PTP-N, Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, PTPRN, ICA3, ICA512
Entrez GeneID 5798
Swissprot Q16849
WB Predicted band size 105.8kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This PTPRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-316 amino acids from the Central region of human PTPRN.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

PTPRN Antibody (Center) (Cat. #P31486) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PTPRN antibody detected the PTPRN protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。