Rabbit Polyclonal Antibody to PUF6

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别名:FIR; VRJS; RoBPI; SIAHBP1
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor.

Description

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor.

Specification
Aliases	FIR; VRJS; RoBPI; SIAHBP1
Entrez GeneID	22827;
Swissprot	Q9UHX1
WB Predicted band size	60kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Fusion protein of human PUF60
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/200-1/1000
IHC	1/100-1/200

	Gel: 8%SDS-PAGE Lysate: 40 μg Lane: Mouse brain tissue Primary antibody: 1/400 dilution Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds
	Immunohistochemical analysis of paraffin-embedded Human Breast cancer tissue using P43442 at dilution 1/200.
	Immunohistochemical analysis of paraffin-embedded Human Esophagus cancer tissue using P43442 at dilution 1/200.