别名:RAB3 GTPase activating protein 2 (non-catalytic); RAB3-GAP150; RAB3GAP150; RBGPR; RGAP-iso应用:WB,IHC
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.Nagano F., J. Biol. Chem. 273:24781-24785(1998).Xu X., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.Nagase T., DNA Res. 5:355-364(1998). |
Specification | |
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Aliases | RAB3 GTPase activating protein 2 (non-catalytic); RAB3-GAP150; RAB3GAP150; RBGPR; RGAP-iso |
Entrez GeneID | 25782; |
Swissprot | Q9H2M9 |
WB Predicted band size | 156kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from internal of human. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
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Western blot analysis of extracts from COS cells, using RAB3GAP2 antibody P42543. |
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using RAB3GAP2 antibody P42543. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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