别名:GTP-binding protein RAD; RAD; RAD1; RAS associated with diabetes;应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格:50μl/100μl
Description |
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May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane By similarity. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.Reynet C., Science 262:1441-1444(1993).The MGC Project Team; Genome Res. 14:2121-2127(2004).Moyers J.S., J. Biol. Chem. 272:11832-11839(1997). |
Specification | |
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Aliases | GTP-binding protein RAD; RAD; RAD1; RAS associated with diabetes; |
Entrez GeneID | 6236; |
Swissprot | P55042 |
WB Predicted band size | 33kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide derived from internal of human RAD. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
ICC | 1/100-1/500 |
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Western blot analysis of extracts from HeLa cells, HepG2 cells and MCF-7 cells, using RAD antibody P42428. |
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Immunofluorescence analysis of A549 cells, using RAD antibody P42428. |
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Immunohistochemistry analysis of paraffin-embedded human heart tissue using RAD antibody P42428. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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