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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to RAD51C

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别名:DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene is a member of the RAD51 family of related
genes, which encode strand-transfer proteins thought to be involved
in recombinational repair of damaged DNA and in meiotic
recombination. This gene product interacts with two other DNA
repair proteins, encoded by RAD51B and XRCC3, but not with itself.
The protein copurifies with XRCC3 protein in a complex, reflecting
their endogenous association and suggesting a cooperative role
during recombinational repair. This gene is one of four localized
to a region of chromosome 17q23 where amplification occurs
frequently in breast tumors. Overexpression of the four genes
during amplification has been observed and suggests a possible role
in tumor progression. Alternative splicing has been observed for
this gene and two variants encoding different isoforms have been
identified.
Specification
Aliases DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2
Entrez GeneID 5889
Swissprot O43502
WB Predicted band size 42.2kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

RAD51C Antibody (Center) (Cat. #P31566) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RAD51C antibody detected the RAD51C protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。