别名:DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2应用:WB
反应种属:Human
规格:50μl/100μl
| Description |
|---|
| This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. |
| Specification | |
|---|---|
| Aliases | DNA repair protein RAD51 homolog 3, R51H3, RAD51 homolog C, RAD51-like protein 2, RAD51C, RAD51L2 |
| Entrez GeneID | 5889 |
| Swissprot | O43502 |
| WB Predicted band size | 42.2kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RAD51C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human RAD51C. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
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RAD51C Antibody (Center) (Cat. #P31566) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RAD51C antibody detected the RAD51C protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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