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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to RAMP3

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别名:Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
The protein encoded by this gene is a member of the RAMP
family of single-transmembrane-domain proteins, called receptor
(calcitonin) activity modifying proteins (RAMPs). RAMPs are type I
transmembrane proteins with an extracellular N terminus and a
cytoplasmic C terminus. RAMPs are required to transport
calcitonin-receptor-like receptor (CRLR) to the plasma membrane.
CRLR, a receptor with seven transmembrane domains, can function as
either a calcitonin-gene-related peptide (CGRP) receptor or an
adrenomedullin receptor, depending on which members of the RAMP
family are expressed. In the presence of this (RAMP3) protein, CRLR
functions as an adrenomedullin receptor.
Specification
Aliases Receptor activity-modifying protein 3, Calcitonin-receptor-like receptor activity-modifying protein 3, CRLR activity-modifying protein 3, RAMP3
Entrez GeneID 10268
Swissprot O60896
WB Predicted band size 16.5kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen This RAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the C-terminal region of human RAMP3.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

Anti-RAMP3 Antibody (C-term) at 1:1000 dilution + human lung lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 17 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

RAMP3 Antibody (C-term) (Cat. #P33761) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the RAMP3 antibody detected the RAMP3 protein (arrow).
RAMP3 Antibody (C-term) (Cat. #P33761) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the RAMP3 antibody detected the RAMP3 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。