Rabbit Polyclonal Antibody to RAP2A

包装: 1G|100G|500G|1KG|100KG

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别名:Ras-related protein Rap-2a, RbBP-30, RAP2A
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Description

Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Specification
Aliases	Ras-related protein Rap-2a, RbBP-30, RAP2A
Entrez GeneID	5911
Swissprot	P10114
WB Predicted band size	20.6kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This RAP2A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 124-159 amino acids from human RAP2A.