Rabbit Polyclonal Antibody to RBBP7

包装: 1G|100G|500G|1KG|100KG

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别名:Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Description

This protein is a ubiquitously expressed nuclear protein
and belongs to a highly conserved subfamily of WD-repeat proteins.
It is found among several proteins that binds directly to
retinoblastoma protein, which regulates cell proliferation. The
encoded protein is found in many histone deacetylase complexes,
including mSin3 co-repressor complex. It is also present in protein
complexes involved in chromatin assembly. This protein can interact
with BRCA1 tumor-suppressor gene and may have a role in the
regulation of cell proliferation and differentiation. Two
transcript variants encoding different isoforms have been found for
this gene.

Specification
Aliases	Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46
Entrez GeneID	5931
Swissprot	Q16576
WB Predicted band size	47.8kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This RBBP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the Central region of human RBBP7.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000

	RBBP7 Antibody (Center) (Cat. #P31610) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RBBP7 antibody detected the RBBP7 protein (arrow).
	Western blot analysis of RBBP7 (arrow) using rabbit polyclonal RBBP7 Antibody (Center) (Cat. #P31610). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the RBBP7 gene.