别名:RIM; COM1; CTIP; JWDS; SAE2; SCKL2应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. |
Specification | |
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Aliases | RIM; COM1; CTIP; JWDS; SAE2; SCKL2 |
Entrez GeneID | 5932; |
Swissprot | Q99708 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein corresponding to residues near the C terminal of human retinoblastoma binding protein 8 |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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IHC | 1/100-1/300 |
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42820 at dilution 1/65. |
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Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using P42820 at dilution 1/65. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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